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MOLECULAR BIOPHYSICS AND MEDICAL PHYSICS LABORATORY
Alexandru Ioan Cuza University of Iasi
Short link:
https://eeris.eu/
ERIF-2000-000Q-0703
2887
Visits
The paradigms approached in our group seek to bring novel insights towards a better understanding of phenomena occurring at the cellular membrane level, which involve interactions between membrane active peptides, small bioactive molecules and lipid-protein systems, and try to envision new approaches useful for biosensing, biomedical assays and diagnosis. The social and scientific impact of our studies is outlined by the ability to rationally design and test new therapeutic agents with improved ...
Tudor
Luchian
luchian@uaic.ro
Professor PhD
SCIENTIFIC TEAM
5
Alina ASANDEI
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Corina CIOBANASU
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Isabela DRAGOMIR
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Loredana MEREUTA
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Irina SCHIOPU
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Biomedical Imaging Facilities
RI Domain of activity
Micro and Nanotechnology Facilities
RI Domain of activity
Single-molecule biophysics; Monitoring of protein properties via electrophysiology and fluorescence
RI Domain of activity
Type Of RI:
Single sited RI
RI Life Cycle Status:
Active RI
Research Data Management Plan:
No information available
Access Policy to Research Infrastructure and Related Services:
No information available
Research Services
Molecular biophysics and medical physics
SERVICE DESCRIPTION:
We could offer top-notch quality assistance in relevant scientific topics.
SERVICE PERSONS:
Alina ASANDEI
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Irina SCHIOPU
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Corina CIOBANASU
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Loredana MEREUTA
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Isabela DRAGOMIR
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Protein electrophysiology
SERVICE DESCRIPTION:
We could offer top-notch quality assistance in relevant scientific topics.
SERVICE PERSONS:
Alina ASANDEI
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Irina SCHIOPU
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Corina CIOBANASU
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Loredana MEREUTA
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Isabela DRAGOMIR
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Single molecule recordings
SERVICE DESCRIPTION:
We could offer top-notch quality assistance in relevant scientific topics.
SERVICE PERSONS:
Alina ASANDEI
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Irina SCHIOPU
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Corina CIOBANASU
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Loredana MEREUTA
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Isabela DRAGOMIR
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Ion channels reconstitution and analysis
SERVICE DESCRIPTION:
We could offer top-notch quality assistance in relevant scientific topics.
SERVICE PERSONS:
Alina ASANDEI
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Irina SCHIOPU
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Corina CIOBANASU
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Loredana MEREUTA
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Isabela DRAGOMIR
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The interaction of antimicrobial peptides with lipid membranes
SERVICE DESCRIPTION:
We could offer top-notch quality assistance in relevant scientific topics.
SERVICE PERSONS:
Alina ASANDEI
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Irina SCHIOPU
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Corina CIOBANASU
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Loredana MEREUTA
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Isabela DRAGOMIR
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Biosensing of toxic and warfare agents
SERVICE DESCRIPTION:
We could offer top-notch quality assistance in relevant scientific topics.
SERVICE PERSONS:
Alina ASANDEI
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Irina SCHIOPU
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Corina CIOBANASU
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Loredana MEREUTA
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Isabela DRAGOMIR
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Research Equipment
Axopatch 200B Amplifier
CATALOG NAME:
Axopatch 200B Amplifier
DESCRIPTION:
The benchmark for single-channel recordings and other applications where an excellent signal-to-noise ratio is key.
PRODUCER:
Molecular Devices, USA
PRODUCTION YEAR:
2003
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Nanoject II Single Line Nanoliter Injection (hydraulic)
CATALOG NAME:
Nanoject II Single Line Nanoliter Injection (hydraulic)
DESCRIPTION:
It is a precision, high quality instrument designed to provide superior microinjection performance.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2003
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Epifluorescence, Zeiss Axiovert 40CFL microscope
CATALOG NAME:
Epifluorescence, Zeiss Axiovert 40CFL microscope
DESCRIPTION:
PRODUCER:
Carl Zeiss
PRODUCTION YEAR:
2004
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Model SC 20 Solution In Line Heater Cooler Two Line
CATALOG NAME:
In-line Heater/Cooler (SC-20)
DESCRIPTION:
This dual in-line solution heater/cooler extends the temperature range for controlled perfusion studies of both coverslip mounted cells and anchored tissue thin slices.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2005
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
MultiClamp 700B Amplifier
CATALOG NAME:
MultiClamp 700B Amplifier
DESCRIPTION:
For single-channel recordings, whole-cell voltage- and current-clamp recordings, intracellular sharp electrode recordings, extracellular field potential recordings in ion channel, neuroscience, nanopore, voltammetry studies
PRODUCER:
Molecular Devices, USA
PRODUCTION YEAR:
2006
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Model CL 100 Bipolar Peltier device Temperature Controller
CATALOG NAME:
Bipolar Temperature Controller (CL-100)
DESCRIPTION:
The CL-100 Temperature Controller is an automatic single channel controller capable of accurately maintaining a Peltier device between 0° and +50°C, or a resistive heating element between ambient and +65°C.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2007
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
SUNStir 3 System for Planar Lipid Bilayer Workstation
CATALOG NAME:
SUNStir 3 System for Planar Lipid Bilayer Workstation
DESCRIPTION:
The SUNStir-3 System is comprised of the SUNStir controller, a SUN-1 lamp and a SPIN-2 stirplate. This convenient, rack-mountable system is designed to provide simultaneous control for both the SUN-1 lamp and the SPIN-2 stirplate.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2008
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Electrometer Intracellular Amplifier IE 210
CATALOG NAME:
Intracellular Electrometer (IE-210
DESCRIPTION:
A high impedance electrometer designed specifically for intracellular studies. The instrument consists of two sections; the probe headstage and the controller which contains the signal conditioning, monitoring and power circuitry.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2008
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Quick Exchange Heated Cooled Platform for 35 mm Petri Dishes
CATALOG NAME:
Quick Exchange Heated / Cooled Platform for 35 mm Petri Dishes (QE-1HC)
DESCRIPTION:
Designed for use with 35 mm Petri dishes and Series 40 quick change imaging chambers, Open design for easy cell access, Dish adapters for all major brand 35 mm dishes, Temperature control from 5° to 50°C.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2009
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Ultraprecise Motorized Micromanipulator
CATALOG NAME:
Ultraprecise Motorized Micromanipulator
DESCRIPTION:
This ultraprecise manual micromanipulator has a mass of 6 kg and solid workmanship to support the most precise movement with a minimum of hand-transmitted vibration, backlash or drift. The instrument can be used alone or can serve as an ideal mount for even more precise microdrives.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2010
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Neo sCMOS ANDOR camera
CATALOG NAME:
Neo sCMOS ANDOR camera
DESCRIPTION:
Andor's multi-megapixel sCMOS cameras are unique in their ability to combine ultra-low noise, extremely rapid frame rates, wide dynamic range, large field of view and high-resolution.
PRODUCER:
Andor Technology
PRODUCTION YEAR:
2011
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Universal 320R centrifuge
CATALOG NAME:
UNIVERSAL 320/320 R Benchtop Centrifuges
DESCRIPTION:
The UNIVERSAL 320 offers laboratories a true workflow benefit due to its vast capabilities as mid-sized, general purpose, tabletop centrifuge. Available with temperature control, the UNIVERSAL 320R refrigerated centrifuge offers a unique fast-cool function that will lower the unit to +4 °C in 10-15 minutes saving you valuable time spinning delicate samples.
PRODUCER:
Hettich, Germany
PRODUCTION YEAR:
2012
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Planar Lipid Bilayer Thermocycler
CATALOG NAME:
Planar Lipid Bilayer Thermocycler
DESCRIPTION:
The BLM-TC from Warner Instruments uses Peltier technology to reliably cool, heat, or thermocycle a planar bilayer membrane. The tight and reproducible temperature control provided by this unique device can facilitate the measurement of single channel events at physiologic temperatures, or at any temperature between 5 and 50 °C.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2013
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
PIP 5 pipette puller
CATALOG NAME:
PIP 5 pipette puller
DESCRIPTION:
The PIP 5 is a temperature controlled puller which is a further step to make pulling of glass pipettes easier and more comfortable in the sense of a better reproducibility. It was developed for pulling glass pipettes as they are used for clamp experiments. The range of application of the produced pipettes covers e.g. intracellular recording pipettes or patch-clamp pipettes. The pipettes are being produced by a 2-step vertical pull at different temperatures and pull lengths. Due to the symmetry of the pull you will always receive two equivalent pipettes.
PRODUCER:
HEKA
PRODUCTION YEAR:
2009
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
EPC8 patch-clamp amplifier
CATALOG NAME:
EPC8 patch-clamp amplifier
DESCRIPTION:
The EPC 8 is a manually or computer controlled patch clamp amplifier for… • High time resolution low noise single-channel, wholecell, and loose patch recordings • Voltage clamp and current clamp studies • Recordings from artificial membranes
PRODUCER:
HEKA
PRODUCTION YEAR:
2010
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Low Pass Filter DC Intracellular Extracellular Amplifier Model LPF 8
CATALOG NAME:
Low Pass Filter DC Intracellular Extracellular Amplifier Model LPF 8
DESCRIPTION:
The LPF-8 is the premier low-pass Bessel filter from Warner Instruments and provides superior control of analog signal filtering from 0.1 Hz to 20 kHz. The instrument incorporates low-pass signal filtering and output gains from 1 to 200. Dual selectable signal inputs allow the instrument to be configured to operate in normal, inverted or differential modes. Provides greater frequency control for Bilayer and Oocyte Clamps.
PRODUCER:
Warner Instruments, LLC, USA
PRODUCTION YEAR:
2012
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
FluoroMax-4 Spectrofluorometer
CATALOG NAME:
FluoroMax-4 Spectrofluorometer
DESCRIPTION:
FluoroMax-based solutions are available for measuring solid and liquid samples, with high throughput screening, cryogenic or elevated temperatures, absolute quantum yields, microliter volumes, stopped flow mixing or titration, and even micron scale measurements using a microscope.
PRODUCER:
HORIBA Scientific
PRODUCTION YEAR:
2012
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
Inverted confocal microscope Nikon Ti-E
CATALOG NAME:
Inverted confocal microscope Nikon Ti-E
DESCRIPTION:
In a conventional widefield microscope, the entire specimen is bathed in light from a mercury or xenon source, and the image can be viewed directly by eye or projected directly onto an image capture device. In contrast, in a laser scanning confocal microscope (LSCM) the illumination is achieved by scanning one or more focused beams of light, usually from a laser, across the specimen.
PRODUCER:
Nikon
PRODUCTION YEAR:
2013
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
General electrophysiology instruments
CATALOG NAME:
DESCRIPTION:
LabVIEW-based data acquisition systems, NI PCI-USB data acquisition boards, Tektronix digital oscilloscopes with data processing units, analog and digital signal generators, Keithley electrometer model 6517A
PRODUCER:
PRODUCTION YEAR:
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
General biochemistry instruments
CATALOG NAME:
DESCRIPTION:
UV-VIS spectrophotometers, magnetic stirrers with digital temperature control, pH meters, conductometer, IKA Digital Block Heater, digital balances, vortex mixers, digital pipettes
PRODUCER:
PRODUCTION YEAR:
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
DATA SHEET:
MicroCal PEAQ-ITC
CATALOG NAME:
MicroCal PEAQ-ITC
DESCRIPTION:
The MicroCal PEAQ-ITC is a highly sensitive, low volume isothermal titration calorimeter for the label-free in solution study of biomolecular interactions. It delivers direct measurement of all binding parameters in a single experiment and can analyze weak to high affinity binders, using as little as 10µg sample.
PRODUCER:
Malvern Instruments Limited, Precision Instrumentation and Controls Company
PRODUCTION YEAR:
2018
COMMISSIONING DATE:
PRICE RANGE (at the time of purchase)
100.001 € – 500.000 €
DATA SHEET:
Download data sheet file (2907.66 kb)
Phone:
+40(232)201191
Fax:
+40 (232) 201201
Carol I
,
11
,
Iasi
700506
,
Iasi
Romania
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